Using Nootropics for Anxiety

Using Nootropics for Anxiety

With the many stressors people have weighing them down these days, anxiety is definitely a prevalent condition in many people. You can’t help but worry about your health, finances, work and kids and by doing letting yourself experience anxiety, you in turn make yourself even more sick and anxious. Anxiety impacts your life by decreasing your social connections, slowing down your performance at work and causing problems in your relationships. People who experience anxiety become reactive and in turn relationships, work and school will suffer.

A Natural Approach

Before you head to your doctor to get the latest anti-depressant or anti-anxiety medication that could be full of unwanted side effects, you might want to go a more natural route, using nootropics to combat or relieve your anxiety issues. By using nootropics rather than Benzodiazepines or SSRIs, you won’t experience the brain fog, insomnia or the drug tolerance that commonly comes with the use of these drugs and you also won’t need to get a prescription. But, you should get the advice of a naturopath or other medical doctor before beginning any drug regime to combat your anxiety.

{COPY FOR GRAPHIC} Combat your anxiety using nootropics. We talk about how they work and the best ones to use.

How do Nootropics Work?

Nootropics work by changing the brain chemistry and optimizing the levels of neurotransmitters in the brain to help your specific ailment. For anxiety, anxiolytic nootropics increase the efficiency of specific neurotransmitters like serotonin, dopamine and GABA, to calm the brain and central nervous system, providing mood and stress relief. Using nootropics for anxiety, you’ll feel more relaxed, with less social anxiety and shyness as well.

Serotonin’s Effect

A key link to your mood, happiness and outlook, serotonin plays a large role in your brain’s ability to release anxiety. But, serotonin doesn’t work alone in controlling anxiety – there are other building blocks needed to achieve calmness and decreased anxiety. L-tryptophan and 5-HTP are the most helpful, along with Vitamin B6 in optimizing the natural serotonin levels in the brain. Studies show that taking 5-HTP improves mood in the majority of people who take it.

Dopamine’s Role

There needs to be optimal levels of dopamine in the brain for social function – too little and concentration on social situation will be strained and too much will increase anxiety and lead to avoidance of social situations. Dopamine is known as the reward or pleasure centre of the brain and low dopamine is often to blame in many mood disorders.

What is GABA?

GABA deficiency in the brain is viewed as one of the main causes of anxiety in people. When you have low GABA levels, your nerve cells will transmit more frequent anxiety signals to your body and you’ll experience general nervousness and even panic attacks and compulsive behaviours. Optimizing your GABA levels and activating the GABA receptors by using nootropics will definitely decrease anxiety, but again, GABA doesn’t work alone. GABA precursors or intermediaries are needed to help penetrate the blood-brain barrier.

Using Phenibut to Control Anxiety

Seen as one of the best nootropics for decreasing anxiety, Phenibut is a derivative of GABA and provides a sedative effect, similar to that of drinking alcohol. It has a loose association with benzodiazepines, which cause dependence and withdrawal symptoms, so it shouldn’t be used for long-term use, but is great for serious, but short-term anxiety (i.e., before or during a stressful life event) or to get you to sleep, where you will sleep deeply and restfully. Phenibut was developed for astronauts to deal with stress. Along with stimulating GABA production, it will also increase dopamine levels. This is almost an added layer increasing the calm and feeling of well-being.

There are some side effects to using Phenibut, which include developing a tolerance to the nootropic after a few days of consecutive use, and leading to increased usage for the same initial effect. Withdrawal is also a possibility, leading to increased anxiety after the nootropic is discontinued. To counteract these effects, Phenibut can be cycled and the recommended dosages shouldn’t be exceeded.

Other Nootropics to Combat Anxiety


This nootropic has an indirect effect on GABA levels as it stimulates the receptors that control Glutamate, which is important in the production of GABA. Responses to this nootropic have been mixed, where it is quite a powerful force in some people and has no effect in others.


Noopept also stimulates the receptors to increase Glutamate, which again helps produce GABA in the brain. As well, this nootropic will increase the dopamine and serotonin in the brain, leading to increased calm and reduced anxiety.


For increased energy levels, Picamilon acts like a stimulant, as opposed to Phenibut, which acts like a sedative. It uses vitamin B3 and GABA.


Used to improve mood almost immediately, this nootropic can cross the blood-brain barrier and increase GABA.

Herbs and Minerals that Decrease Anxiety

There are various herbs and minerals used in nootropic supplements along with the above that contribute to the reduction of anxiety in the people that use them. These include:

  • Valerian Root Extract – used for centuries to decrease restlessness and doesn’t affect alertness or concentration
  • Chamomile Flower Extract – used for its calming properties since the times of Ancient Greece
  • Lemon Balm Leaf Extract – aids in maintaining a positive mood and can reduce mental stress when used in conjution with Valerian Root
  • Jujube Seed Extract – this extract can be used for occasional restlessness
  • Vitamin D3 – supports your body’s blood levels of calcium and phosphorus
  • Magnesium – supports your entire body’s basic functioning from your heart to your nervous system, giving a sense of muscular and general physical calming and used to decrease stress and restlessness
  • Vitamin B3 – restores and cleanses the system
  • Tryptophan – a building block for 5-HTP, it aids in sleep and decreases restlessness
  • Vitamin B6 – manufactures amino acid and neurotransmitters like serotonin
  • 5-HTP – optimizes the body’s supply of serotonin

Nootropics can be a very helpful natural remedy for anxiety when you use only the best nootropics. Do your research on nootropic drugs to find the best nootropics for your anxiety issues.