The Best Nootropics for Muscle Growth

Athletes have been using supplements for years, to increase their muscle mass, speed and agility. But, did you know that these supplements are also called nootropics? Nootropics are natural supplements that work with your brain’s chemistry to aid you in whatever you want it to aid you with. There are some great nootropics out there for people looking to help with their workout regime.


Developed in the Soviet Union in the 1960s, this experimental drug was actually used for calming psychiatric children. Later, it was mandated to calm astronauts during space flights. This smart drug has been extensively studied and is now seen as a mood enhancer, sleep aid and helps with recovery from a number of ailments.

Phenibut is associated with GABA, which is a neurotransmitter in the brain that basically controls the central nervous system. It has multiple uses as a nootropic, but since you are reading this guide, you are probably wondering how it helps with muscle growth.

Studies have shown that Phenibut increased resting growth hormone concentrations and post-exercise growth hormone concentration in weight training men. This means your growth hormones work much better after you’ve weight trained when taking this nootropic. Phenibut also helps increase your body’s tolerance to metabolic stress, allowing you train better and harder by preventing the muscle from becoming hypoxic (after not getting enough oxygen).

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Phenibut works best in lean people as it counteracts the natural decrease in growth hormone production, which happens when you are lean.

Phenibut has no psychological side effects, except when people take more than the recommended dose. Studies have only researched doses up to 3 grams per day, so taking more than this is of your own risk. Talking to a naturopathic doctor or other type of healthcare professional is prudent before starting Phenibut, especially when using it for improving muscle growth.

While Phenibut is the main smart drug for improving your physical fitness, it doesn’t always work alone and isn’t the only player on the smart drug market. There are quite a few other nootropics that help improve physical fitness and muscle strength.


Choline is a precursor to the neurotransmitter Acetylcholine, and many people are deficient in it. You can get Choline into your body from food sources, with eggs being the most common (and maybe why many bodybuilders eat a crazy amount of eggs), but you would need to eat more than most people would consume to increase your levels. That said, you can also take Choline supplements, but they work best when combined with Racetams.


Creatine is immensely popular in the gyms as it has the ability to maximize your strength and increase new growth in the muscle. Creatine stores in your body are required to provide energy to your muscle during weight training sets. If you are lacking in the creatine department, you won’t be able to lift as much or for as long. Many bodybuilders take creatine before a workout to ensure the stores are full, which allows them to lift as much as possible for as long as possible.


Drinking coffee and taking caffeine nootropics have very different effects on the body. While both are a stimulant and increase metabolism, taking caffeine before a workout can dramatically improve your energy and actually burn fat. It does this by releasing fatty acids into the blood stream to be used as energy. Caffeine will also give you energy and increase focus, which can be a definite advantage when doing a weight-training regime. But, there is such a thing as too much when it comes to caffeine, as many people probably already know. In the fitness sense, taking high doses of caffeine, your performance can be dramatically impaired. You’ll also want to take your caffeine at least 30 minutes before a workout as the effects sometimes take time to work.


This nootropic is known for boosting athletic performance, along with enhancing cognitive function. It helps to burn stored fat and improve energy levels, both of which are important in a fitness routine. While burning fat for energy, it doesn’t use your glucose stores, which means you keep an even blood sugar during workouts. Acetyl-L-Carnitine also boosts testosterone in those that use it, which can help to increase your muscle and bone mass when working out. It is recommended that you split your daily dose to half before a workout and half after to get the best effects and that you take it with food. A great side effect that comes from using this nootropic is that it is also an antioxidant, which means it will remove toxins from your body, built up from doing your workouts or from other non-fitness activities. It crosses the blood-brain barrier and naturally calms and focuses users, which can help with motivation for working out.


As one of the most common nootropics on the market, Piracetam is very widely-used for a number of ailments, including its ability to improve focus and motivation. Both focus and motivation are important precursors to a fitness regime, as it gets you to the gym! Besides this, it actually improves your muscle memory, which can result in increased muscle growth over a shorter time.

Taking nootropics for muscle growth is definitely something that novices and pros should research to decide if it is right for them. You can see vast improvements just from one of the nootropics on this list, but also from combining them, and finding the right nootropic stack for your body type and what results you are looking to achieve.